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Effect of the Phosphodiesterase-5 Inhibitor Zaprinast on Ischemia-Reperfusion Injury in Rats

PURPOSE: The cardiac and renal protective effects of phosphodiesterase-5 (PDE-5) inhibitors against ischemia-reperfusion injury have recently been demonstrated in animal studies. We evaluated the effect of pretreatment with the PDE-5 inhibitor zaprinast on warm renal ischemia in a rat model. METHODS...

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Detalhes bibliográficos
Main Authors: Polcari, Anthony J., Farooq, Ahmer V., Woods, Michael E., Ripsch, Matthew S., Picken, Maria, Turk, Thomas M.T., White, Fletcher A.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608021/
https://ncbi.nlm.nih.gov/pubmed/22974473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/end.2012.0198
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