Cyclic Nucleotide Phosphodiesterase 3A1 Protects the Heart Against Ischemia-Reperfusion Injury

Phosphodiesterase 3A (PDE3A) is a major regulator of cAMP in cardiomyocytes. PDE3 inhibitors are used for acute treatment of congestive heart failure, but are associated with increased incidence of arrhythmias and sudden death with long-term use. We previously reported that chronic PDE3A downregulat...

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Bibliographische Detailangaben
Hauptverfasser: Oikawa, Masayoshi, Wu, Meiping, Lim, Soyeon, Knight, Walter E., Miller, Clint L., Cai, Yujun, Lu, Yan, Blaxall, Burns C., Takeishi, Yasuchika, Abe, Jun-ichi, Yan, Chen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869570/
https://ncbi.nlm.nih.gov/pubmed/23988739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2013.08.003
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