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The effect of C1 inhibitor on myocardial ischemia and reperfusion injury

BACKGROUND: Activation of the complement system has been demonstrated to be an important mechanism in the mediation of myocardial ischemia and reperfusion (MIR) injury. C1 inhibitor (C1INH) has been shown to be beneficial in experimental MIR models. The underlying mechanism of this effect has been a...

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Autori principali: Lu, Fengxin, Fernandes, Stacey M., Davis, Alvin E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449044/
https://ncbi.nlm.nih.gov/pubmed/22705194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carpath.2012.05.003
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