Pretreatment with a Phosphodiesterase-3 Inhibitor, Milrinone, Reduces Hepatic Ischemia-Reperfusion Injury, Minimizing Pericentral Zone-Based Liver and Small Intestinal Injury in Rats

BACKGROUND: Severe pericentral zone (zone 3)-based liver injury (LI) may become intractable, with allograft dysfunction after liver transplantation. The phosphodiesterase-3 inhibitor, milrinone, has been reported to attenuate hepatic ischemia–reperfusion injury (IRI). This study clarified how hepati...

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Vydáno v:Ann Transplant
Hlavní autoři: Nakanuma, Shinichi, Tajima, Hidehiro, Takamura, Hiroyuki, Sakai, Seisho, Gabata, Ryosuke, Okazaki, Mitsuyoshi, Shinbashi, Hiroyuki, Ohbatake, Yoshinao, Makino, Isamu, Hayashi, Hironori, Miyashita, Tomoharu, Fushida, Sachio, Ohta, Tetsuo
Médium: Artigo
Jazyk:Inglês
Vydáno: International Scientific Literature, Inc. 2020
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Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380127/
https://ncbi.nlm.nih.gov/pubmed/32661218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/AOT.922306
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