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Silica induces NLRP3 inflammasome activation in human lung epithelial cells
BACKGROUND: In myeloid cells the inflammasome plays a crucial role in innate immune defenses against pathogen- and danger-associated patterns such as crystalline silica. Respirable mineral particles impinge upon the lung epithelium causing irreversible damage, sustained inflammation and silicosis. I...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3607900/ https://ncbi.nlm.nih.gov/pubmed/23402370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-8977-10-3 |
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