Differences in gene expression and cytokine production by crystalline vs. amorphous silica in human lung epithelial cells

BACKGROUND: Exposure to respirable crystalline silica particles, as opposed to amorphous silica, is associated with lung inflammation, pulmonary fibrosis (silicosis), and potentially with lung cancer. We used Affymetrix/GeneSifter microarray analysis to determine whether gene expression profiles dif...

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Detalhes bibliográficos
Main Authors: Perkins, Timothy N, Shukla, Arti, Peeters, Paul M, Steinbacher, Jeremy L, Landry, Christopher C, Lathrop, Sherrill A, Steele, Chad, Reynaert, Niki L, Wouters, Emiel FM, Mossman, Brooke T
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337246/
https://ncbi.nlm.nih.gov/pubmed/22300531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-8977-9-6
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