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Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses

Identification of complex molecular networks underlying common human phenotypes is a major challenge of modern genetics. In this study we develop a method for NETwork-Based Analysis of Genetic associations (NETBAG). We use NETBAG to identify a large biological network of genes affected by rare de no...

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Bibliografiset tiedot
Päätekijät: Gilman, Sarah R., Iossifov, Ivan, Levy, Dan, Ronemus, Michael, Wigler, Michael, Vitkup, Dennis
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607702/
https://ncbi.nlm.nih.gov/pubmed/21658583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.05.021
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