Leveraging blood serotonin as an endophenotype to identify de novo and rare variants involved in autism

BACKGROUND: Autism spectrum disorder (ASD) is one of the most highly heritable neuropsychiatric disorders, but underlying molecular mechanisms are still unresolved due to extreme locus heterogeneity. Leveraging meaningful endophenotypes or biomarkers may be an effective strategy to reduce heterogene...

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Bibliographic Details
Published in:Mol Autism
Main Authors: Chen, Rui, Davis, Lea K., Guter, Stephen, Wei, Qiang, Jacob, Suma, Potter, Melissa H., Cox, Nancy J., Cook, Edwin H., Sutcliffe, James S., Li, Bingshan
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5361831/
https://ncbi.nlm.nih.gov/pubmed/28344757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13229-017-0130-3
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