Leveraging blood serotonin as an endophenotype to identify de novo and rare variants involved in autism

BACKGROUND: Autism spectrum disorder (ASD) is one of the most highly heritable neuropsychiatric disorders, but underlying molecular mechanisms are still unresolved due to extreme locus heterogeneity. Leveraging meaningful endophenotypes or biomarkers may be an effective strategy to reduce heterogene...

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Detalhes bibliográficos
Publicado no:Mol Autism
Main Authors: Chen, Rui, Davis, Lea K., Guter, Stephen, Wei, Qiang, Jacob, Suma, Potter, Melissa H., Cox, Nancy J., Cook, Edwin H., Sutcliffe, James S., Li, Bingshan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5361831/
https://ncbi.nlm.nih.gov/pubmed/28344757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13229-017-0130-3
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