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Exploiting Acyl and Enol Azolium Intermediates via NHeterocyclic Carbene Catalyzed Reactions of Alpha-Reducible Aldehydes

N-heterocyclic carbenes are well known for their role in catalyzing benzoin and Stetter reactions: the generation of acyl anion equivalents from simple aldehydes to react with a variety of electrophiles. However, when an aldehyde bearing a leaving group or unsaturation adjacent to the acyl anion equ...

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Main Authors: Vora, Harit U., Wheeler, Philip, Rovis, Tomislav
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607462/
https://ncbi.nlm.nih.gov/pubmed/23538785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adsc.201200031
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