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‘Nurr’ishing T(reg) cells: Nr4a transcription factors control Foxp3 expression

The Nr4a family of transcription factors transactivate expression of the transcription factor Foxp3 and are essential for the generation of regulatory T cells. Mice deficient in all three members of the Nr4a family develop massive multiorgan inflammation.

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Detalhes bibliográficos
Main Authors: Bandukwala, Hozefa S, Rao, Anjana
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607440/
https://ncbi.nlm.nih.gov/pubmed/23416671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2546
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