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‘Nurr’ishing T(reg) cells: Nr4a transcription factors control Foxp3 expression
The Nr4a family of transcription factors transactivate expression of the transcription factor Foxp3 and are essential for the generation of regulatory T cells. Mice deficient in all three members of the Nr4a family develop massive multiorgan inflammation.
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3607440/ https://ncbi.nlm.nih.gov/pubmed/23416671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2546 |
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