CD44 expression positively correlates with Foxp3 expression and suppressive function of CD4(+ )T(reg )cells

BACKGROUND: CD4(+)CD25(+ )regulatory T (T(reg)) cells develop in the thymus and can suppress T cell proliferation, modulated by Foxp3 and cytokines; however, the relevance of CD44 in T(reg )cell development is less clear. To address this issue, we analyzed Foxp3 expression in CD44(+ )T(reg )cells by...

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Main Authors: Liu, Tie, Soong, Lynn, Liu, Gang, König, Rolf, Chopra, Ashok K
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2009
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770033/
https://ncbi.nlm.nih.gov/pubmed/19852824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-4-40
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