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CD117(+)CD44(+) Stem T Cells Develop in the Thymus and Potently Suppress T-cell Proliferation by Modulating the CTLA-4 Pathway
BACKGROUND: CD117 is expressed on double-negative (DN; CD4(–)CD8(–)) cells (Nat Rev Immunol 14:529–545; 2014), but whether it is expressed in other stages and its subsequent functions are unclear. We used an improved method of flow cytometry to analyze different populations of thymocytes (Sci Rep 4:...
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| Publicado en: | Stem Cell Res Ther |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5345162/ https://ncbi.nlm.nih.gov/pubmed/28279199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0495-4 |
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