MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) PROMOTER POLYMORPHISMS AND SUSCEPTIBILITY TO SEVERE MALARIAL ANEMIA

BACKGROUND: Severe malarial anemia (SMA) resulting from Plasmodium falciparum infections is one of the leading causes of childhood mortality in sub-Saharan Africa. The innate immune mediator, macrophage migration inhibitory factor (MIF) plays a critical role in the pathogenesis of SMA. METHODS: To i...

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Main Authors: Awandare, Gordon A., Martinson, Jeremy J., Were, Tom, Ouma, Collins, Davenport, Gregory C., Ong’echa, John M., Wang, Wen Kui, Leng, Lin, Ferrell, Robert E., Bucala, Richard, Perkins, Douglas J.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607439/
https://ncbi.nlm.nih.gov/pubmed/19591577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/600894
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