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Cellular Strategies for Regulating Functional and Nonfunctional Protein Aggregation

Growing evidence suggests that aggregation-prone proteins are both harmful and functional for a cell. How do cellular systems balance the detrimental and beneficial effect of protein aggregation? We reveal that aggregation-prone proteins are subject to differential transcriptional, translational, an...

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Detalles Bibliográficos
Main Authors: Gsponer, Jörg, Babu, M. Madan
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607227/
https://ncbi.nlm.nih.gov/pubmed/23168257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.09.036
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