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Tight regulation of unstructured proteins: from transcript synthesis to protein degradation

Altered abundance of several intrinsically unstructured proteins (IUPs) has been associated with perturbed cellular signalling that may lead to pathological conditions such as cancer. Therefore, it is important to understand how cells precisely regulate availability of IUPs. We observe that regulati...

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Detalhes bibliográficos
Main Authors: Gsponer, Jörg, Futschik, Matthias E., Teichmann, Sarah A., Babu, M. Madan
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803065/
https://ncbi.nlm.nih.gov/pubmed/19039133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1163581
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