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The contribution of intrinsically disordered regions to protein function, cellular complexity, and human disease

In the 1960s, Christian Anfinsen postulated that the unique three-dimensional structure of a protein is determined by its amino acid sequence. This work laid the foundation for the sequence–structure–function paradigm, which states that the sequence of a protein determines its structure, and structu...

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Detalhes bibliográficos
Publicado no:Biochem Soc Trans
Autor principal: Babu, M. Madan
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095923/
https://ncbi.nlm.nih.gov/pubmed/27911701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20160172
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