Three Distinct Patterns of Histone H3Y41 Phosphorylation Mark Active Genes

The JAK2 tyrosine kinase is a critical mediator of cytokine-induced signaling. It plays a role in the nucleus, where it regulates transcription by phosphorylating histone H3 at tyrosine 41 (H3Y41ph). We used chromatin immunoprecipitation coupled to massively parallel DNA sequencing (ChIP-seq) to def...

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Detalhes bibliográficos
Main Authors: Dawson, Mark A., Foster, Samuel D., Bannister, Andrew J., Robson, Samuel C., Hannah, Rebecca, Wang, Xiaonan, Xhemalce, Blerta, Wood, Andrew D., Green, Anthony R., Göttgens, Berthold, Kouzarides, Tony
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2012
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607218/
https://ncbi.nlm.nih.gov/pubmed/22999934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.08.016
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