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L-acetylcarnitine causes rapid antidepressant effects through the epigenetic induction of mGlu2 receptors
Epigenetic mechanisms are involved in the pathophysiology of depressive disorders and are unique potential targets for therapeutic intervention. The acetylating agent L-acetylcarnitine (LAC), a well-tolerated drug, behaves as an antidepressant by the epigenetic regulation of type 2 metabotropic glut...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3607061/ https://ncbi.nlm.nih.gov/pubmed/23382250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216100110 |
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