Nitration of Hsp90 induces cell death

Oxidative stress is a widely recognized cause of cell death associated with neurodegeneration, inflammation, and aging. Tyrosine nitration in these conditions has been reported extensively, but whether tyrosine nitration is a marker or plays a role in the cell-death processes was unknown. Here, we s...

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Main Authors: Franco, Maria Clara, Ye, Yaozu, Refakis, Christian A., Feldman, Jessica L., Stokes, Audrey L., Basso, Manuela, Melero Fernández de Mera, Raquel M., Sparrow, Nicklaus A., Calingasan, Noel Y., Kiaei, Mahmoud, Rhoads, Timothy W., Ma, Thong C., Grumet, Martin, Barnes, Stephen, Beal, M. Flint, Beckman, Joseph S., Mehl, Ryan, Estévez, Alvaro G.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2013
主題:
PNAS Plus
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607042/
https://ncbi.nlm.nih.gov/pubmed/23487751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1215177110
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