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Nitration of Hsp90 induces cell death

Oxidative stress is a widely recognized cause of cell death associated with neurodegeneration, inflammation, and aging. Tyrosine nitration in these conditions has been reported extensively, but whether tyrosine nitration is a marker or plays a role in the cell-death processes was unknown. Here, we s...

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Bibliographische Detailangaben
Hauptverfasser: Franco, Maria Clara, Ye, Yaozu, Refakis, Christian A., Feldman, Jessica L., Stokes, Audrey L., Basso, Manuela, Melero Fernández de Mera, Raquel M., Sparrow, Nicklaus A., Calingasan, Noel Y., Kiaei, Mahmoud, Rhoads, Timothy W., Ma, Thong C., Grumet, Martin, Barnes, Stephen, Beal, M. Flint, Beckman, Joseph S., Mehl, Ryan, Estévez, Alvaro G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607042/
https://ncbi.nlm.nih.gov/pubmed/23487751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1215177110
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