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HSP90 is a chaperone for DLK and is required for axon injury signaling

Peripheral nerve injury induces a robust proregenerative program that drives axon regeneration. While many regeneration-associated genes are known, the mechanisms by which injury activates them are less well-understood. To identify such mechanisms, we performed a loss-of-function pharmacological scr...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Karney-Grobe, Scott, Russo, Alexandra, Frey, Erin, Milbrandt, Jeffrey, DiAntonio, Aaron
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6196532/
https://ncbi.nlm.nih.gov/pubmed/30275300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1805351115
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