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Crucial role of the hydrophobic pocket region of Munc18 protein in mast cell degranulation
The function of the Munc18-1 protein hydrophobic pocket, which interacts with the syntaxin-1 N-terminal peptide, has been highly controversial in neurosecretion. Recent analysis of patients with familial hemophagocytic lymphohistiocytosis type 5 has identified the E132A mutation in the hydrophobic p...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3607013/ https://ncbi.nlm.nih.gov/pubmed/23487749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1214887110 |
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