Dual roles of FBXL3 in the mammalian circadian feedback loops are important for period determination and robustness of the clock

The mammalian circadian clock is composed of interlocking feedback loops. Cryptochrome is a central component in the core negative feedback loop, whereas Rev-Erbα, a member of the nuclear receptor family, is an essential component of the interlocking loop. To understand the roles of different clock...

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Bibliographische Detailangaben
Hauptverfasser: Shi, Guangsen, Xing, Lijuan, Liu, Zhiwei, Qu, Zhipeng, Wu, Xi, Dong, Zhen, Wang, Xiaohan, Gao, Xiang, Huang, Moli, Yan, Jie, Yang, Ling, Liu, Yi, Ptáček, Louis J., Xu, Ying
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606995/
https://ncbi.nlm.nih.gov/pubmed/23471982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1302560110
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