Dual roles of FBXL3 in the mammalian circadian feedback loops are important for period determination and robustness of the clock

The mammalian circadian clock is composed of interlocking feedback loops. Cryptochrome is a central component in the core negative feedback loop, whereas Rev-Erbα, a member of the nuclear receptor family, is an essential component of the interlocking loop. To understand the roles of different clock...

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Detalhes bibliográficos
Main Authors: Shi, Guangsen, Xing, Lijuan, Liu, Zhiwei, Qu, Zhipeng, Wu, Xi, Dong, Zhen, Wang, Xiaohan, Gao, Xiang, Huang, Moli, Yan, Jie, Yang, Ling, Liu, Yi, Ptáček, Louis J., Xu, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606995/
https://ncbi.nlm.nih.gov/pubmed/23471982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1302560110
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