Dual roles of FBXL3 in the mammalian circadian feedback loops are important for period determination and robustness of the clock

The mammalian circadian clock is composed of interlocking feedback loops. Cryptochrome is a central component in the core negative feedback loop, whereas Rev-Erbα, a member of the nuclear receptor family, is an essential component of the interlocking loop. To understand the roles of different clock...

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Dettagli Bibliografici
Autori principali: Shi, Guangsen, Xing, Lijuan, Liu, Zhiwei, Qu, Zhipeng, Wu, Xi, Dong, Zhen, Wang, Xiaohan, Gao, Xiang, Huang, Moli, Yan, Jie, Yang, Ling, Liu, Yi, Ptáček, Louis J., Xu, Ying
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606995/
https://ncbi.nlm.nih.gov/pubmed/23471982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1302560110
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