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Feedback Loops of the Mammalian Circadian Clock Constitute Repressilator

Mammals evolved an endogenous timing system to coordinate their physiology and behaviour to the 24h period of the solar day. While it is well accepted that circadian rhythms are generated by intracellular transcriptional feedback loops, it is still debated which network motifs are necessary and suff...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Pett, J. Patrick, Korenčič, Anja, Wesener, Felix, Kramer, Achim, Herzel, Hanspeter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5189953/
https://ncbi.nlm.nih.gov/pubmed/27942033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005266
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