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Feedback Loops of the Mammalian Circadian Clock Constitute Repressilator

Mammals evolved an endogenous timing system to coordinate their physiology and behaviour to the 24h period of the solar day. While it is well accepted that circadian rhythms are generated by intracellular transcriptional feedback loops, it is still debated which network motifs are necessary and suff...

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Библиографические подробности
Опубликовано в: :PLoS Comput Biol
Главные авторы: Pett, J. Patrick, Korenčič, Anja, Wesener, Felix, Kramer, Achim, Herzel, Hanspeter
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5189953/
https://ncbi.nlm.nih.gov/pubmed/27942033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005266
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