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From mechanical folding trajectories to intrinsic energy landscapes of biopolymers
In single-molecule laser optical tweezer (LOT) pulling experiments, a protein or RNA is juxtaposed between DNA handles that are attached to beads in optical traps. The LOT generates folding trajectories under force in terms of time-dependent changes in the distance between the beads. How to construc...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3606983/ https://ncbi.nlm.nih.gov/pubmed/23487746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1214051110 |
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