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Development of a Cell-Based Functional Assay for the Detection of Clostridium botulinum Neurotoxin Types A and E

The standard procedure for definitive detection of BoNT-producing Clostridia is a culture method combined with neurotoxin detection using a standard mouse bioassay (MBA). The mouse bioassay is highly sensitive and specific, but it is expensive and time-consuming, and there are ethical concerns due t...

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Autori principali: Basavanna, Uma, Muruvanda, Tim, Brown, Eric W., Sharma, Shashi K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606727/
https://ncbi.nlm.nih.gov/pubmed/23533420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/593219
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