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Protein Domain Analysis of C. botulinum Type A Neurotoxin and Its Relationship with Other Botulinum Serotypes

Botulinum neurotoxins (BoNTs) are highly potent poisons produced by seven serotypes of Clostridium botulinum. The mechanism of neurotoxin action is a multistep process which leads to the cleavage of one of three different SNARE proteins essential for synaptic vesicle fusion and transmission of the n...

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Detalhes bibliográficos
Main Authors: Sharma, Shashi K., Basavanna, Uma, Shukla, Hem D.
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206622/
https://ncbi.nlm.nih.gov/pubmed/22069543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins2010001
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