Chromosomal destabilization during gene amplification.
Acentric extrachromosomal elements, such as submicroscopic autonomously replicating circular molecules (episomes) and double minute chromosomes, are common early, and in some cases initial, intermediates of gene amplification in many drug-resistant and tumor cell lines. In order to gain a more compl...
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| Publié dans: | Mol Cell Biol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
1990
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360670/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2188107/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.6.3056-3066.1990 |
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