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Chromosomal destabilization during gene amplification.

Acentric extrachromosomal elements, such as submicroscopic autonomously replicating circular molecules (episomes) and double minute chromosomes, are common early, and in some cases initial, intermediates of gene amplification in many drug-resistant and tumor cell lines. In order to gain a more compl...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Biol
Prif Awduron: Ruiz, J C, Wahl, G M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 1990
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360670/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2188107/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.6.3056-3066.1990
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