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An evolutionarily conserved mode of modulation of Shaw-like K(+) channels

Voltage-gated K(+) channels of the Shaw family (also known as the KCNC or Kv3 family) play pivotal roles in mammalian brains, and genetic or pharmacological disruption of their activities in mice results in a spectrum of behavioral defects. We have used the model system of Caenorhabditis elegans to...

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Autori principali: Cotella, Diego, Hernandez-Enriquez, Berenice, Duan, Zhibing, Wu, Xilong, Gazula, Valeswara-Rao, Brown, Maile R., Kaczmarek, Leonard K., Sesti, Federico
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606535/
https://ncbi.nlm.nih.gov/pubmed/23233530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-222778
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