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Molecular Mechanisms Underlying the Apoptotic Effect of KCNB1 K(+) Channel Oxidation
Potassium (K(+)) channels are targets of reactive oxygen species in the aging nervous system. KCNB1 (formerly Kv2.1), a voltage-gated K(+) channel abundantly expressed in the cortex and hippocampus, is oxidized in the brains of aging mice and of the triple transgenic 3xTg-AD mouse model of Alzheimer...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3567663/ https://ncbi.nlm.nih.gov/pubmed/23275378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.440933 |
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