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Inhibition of topoisomerase II does not inhibit transcription of RNA polymerase I and II genes.

Injection of VM-26 (teniposide) into Xenopus oocytes inhibits the activity of topoisomerase II but does not inhibit transcription by RNA polymerases I and II. A specific assay for topoisomerase II, resolution of catenated DNA molecules into product rings, was used to quantitate VM-26 inhibition in v...

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Vydáno v:Mol Cell Biol
Hlavní autor: Dunaway, M
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 1990
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360651/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2160588/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.6.2893-2900.1990
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