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The Protein Chaperone HSP90 Can Facilitate the Divergence of Gene Duplicates
The heat-shock protein 90 (HSP90) acts as a chaperone by ensuring proper maturation and folding of its client proteins. The HSP90 capacitor hypothesis holds that interactions with HSP90 allow proteins to accumulate mutations while maintaining function. Following this logic, HSP90 clients would be pr...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3606102/ https://ncbi.nlm.nih.gov/pubmed/23410833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.148098 |
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