The Protein Chaperone HSP90 Can Facilitate the Divergence of Gene Duplicates

The heat-shock protein 90 (HSP90) acts as a chaperone by ensuring proper maturation and folding of its client proteins. The HSP90 capacitor hypothesis holds that interactions with HSP90 allow proteins to accumulate mutations while maintaining function. Following this logic, HSP90 clients would be pr...

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Bibliografiska uppgifter
Huvudupphovsmän: Lachowiec, Jennifer, Lemus, Tzitziki, Thomas, James H., Murphy, Patrick J. M., Nemhauser, Jennifer L., Queitsch, Christine
Materialtyp: Artigo
Språk:Inglês
Publicerad: Genetics Society of America 2013
Ämnen:
Investigations
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606102/
https://ncbi.nlm.nih.gov/pubmed/23410833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.148098
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