Hepatitis C virus NS4B targets lipid droplets through hydrophobic residues in the amphipathic helices

Lipid droplets (LD) are dynamic storage organelles that are involved in lipid homeostasis. Hepatitis C virus (HCV) is closely associated with LDs. HCV Core and nonstructural (NS) proteins colocalize with LDs and presumably are involved in virion formation at that site. We demonstrated that HCV NS4B,...

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Bibliografiske detaljer
Main Authors: Tanaka, Torahiko, Kuroda, Kazumichi, Ikeda, Masanori, Wakita, Takaji, Kato, Nobuyuki, Makishima, Makoto
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2013
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605996/
https://ncbi.nlm.nih.gov/pubmed/23315449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M026443
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