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FOLDING AMPHIPATHIC HELICES INTO MEMBRANES: AMPHIPHILICITY TRUMPS HYDROPHOBICITY

High amphiphilicity is a hallmark of interfacial helices in membrane proteins and membrane-active peptides, such as toxins and antimicrobial peptides. Although there is general agreement that amphiphilicity is important for membrane-interface binding, an unanswered question is its importance relativ...

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Detalles Bibliográficos
Main Authors: Fernández-Vidal, Mónica, Jayasinghe, Sajith, Ladokhin, Alexey S., White, Stephen H.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034331/
https://ncbi.nlm.nih.gov/pubmed/17532340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.05.016
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