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Hepatitis C virus NS4B targets lipid droplets through hydrophobic residues in the amphipathic helices
Lipid droplets (LD) are dynamic storage organelles that are involved in lipid homeostasis. Hepatitis C virus (HCV) is closely associated with LDs. HCV Core and nonstructural (NS) proteins colocalize with LDs and presumably are involved in virion formation at that site. We demonstrated that HCV NS4B,...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3605996/ https://ncbi.nlm.nih.gov/pubmed/23315449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M026443 |
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