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Metabolism of oxysterols derived from nonenzymatic oxidation of 7-dehydrocholesterol in cells
Recent studies suggest that 7-dehydrocholesterol (7-DHC)-derived oxysterols play important roles in the pathophysiology of Smith-Lemli-Opitz syndrome (SLOS), a metabolic disorder that is caused by defective 3β-hydroxysterol-Δ(7)-reductase (DHCR7). Although 14 oxysterols have been identified as the p...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Biochemistry and Molecular Biology
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3605989/ https://ncbi.nlm.nih.gov/pubmed/23381570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M035733 |
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