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Lipid biomarkers of oxidative stress in a genetic mouse model of Smith-Lemli-Opitz syndrome
7-Dehydrocholesterol (7-DHC) accumulates in tissues and fluids of patients with Smith-Lemli-Opitz syndrome (SLOS), which is caused by mutations in the gene encoding 3β-hydroxysterol-Δ(7)-reductase (DHCR7). We recently reported that 7-DHC is the most reactive lipid molecule toward free radical oxidat...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3674764/ https://ncbi.nlm.nih.gov/pubmed/22718275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10545-012-9504-z |
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