Macrophage lipoprotein lipase modulates the development of atherosclerosis but not adiposity

The role of macrophage lipoprotein lipase (LpL) in the development of atherosclerosis and adiposity was examined in macrophage LpL knockout (MLpLKO) mice. MLpLKO mice were generated using cre-loxP gene targeting. Loss of LpL in macrophages did not alter plasma LpL activity or lipoprotein levels. Inc...

Full description

Saved in:
Bibliographic Details
Main Authors: Takahashi, Manabu, Yagyu, Hiroaki, Tazoe, Fumiko, Nagashima, Shuichi, Ohshiro, Taichi, Okada, Kenta, Osuga, Jun-ichi, Goldberg, Ira J., Ishibashi, Shun
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2013
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605988/
https://ncbi.nlm.nih.gov/pubmed/23378601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M035568
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items