Macrophage lipoprotein lipase modulates the development of atherosclerosis but not adiposity

The role of macrophage lipoprotein lipase (LpL) in the development of atherosclerosis and adiposity was examined in macrophage LpL knockout (MLpLKO) mice. MLpLKO mice were generated using cre-loxP gene targeting. Loss of LpL in macrophages did not alter plasma LpL activity or lipoprotein levels. Inc...

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Autors principals: Takahashi, Manabu, Yagyu, Hiroaki, Tazoe, Fumiko, Nagashima, Shuichi, Ohshiro, Taichi, Okada, Kenta, Osuga, Jun-ichi, Goldberg, Ira J., Ishibashi, Shun
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2013
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605988/
https://ncbi.nlm.nih.gov/pubmed/23378601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M035568
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