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Macrophage lipoprotein lipase modulates the development of atherosclerosis but not adiposity

The role of macrophage lipoprotein lipase (LpL) in the development of atherosclerosis and adiposity was examined in macrophage LpL knockout (MLpLKO) mice. MLpLKO mice were generated using cre-loxP gene targeting. Loss of LpL in macrophages did not alter plasma LpL activity or lipoprotein levels. Inc...

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Détails bibliographiques
Auteurs principaux: Takahashi, Manabu, Yagyu, Hiroaki, Tazoe, Fumiko, Nagashima, Shuichi, Ohshiro, Taichi, Okada, Kenta, Osuga, Jun-ichi, Goldberg, Ira J., Ishibashi, Shun
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605988/
https://ncbi.nlm.nih.gov/pubmed/23378601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M035568
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