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Dietary manipulation reveals an unexpected inverse relationship between fat mass and adipose 11β-hydroxysteroid dehydrogenase type 1

Increased dietary fat intake is associated with obesity, insulin resistance, and metabolic disease. In transgenic mice, adipose tissue-specific overexpression of the glucocorticoid-amplifying enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) exacerbates high-fat (HF) diet-induced visceral ob...

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Detalhes bibliográficos
Main Authors: Man, Tak Yung, Michailidou, Zoi, Gokcel, Adnan, Ramage, Lynne, Chapman, Karen E., Kenyon, Christopher J., Seckl, Jonathan R., Morton, Nicholas M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605916/
https://ncbi.nlm.nih.gov/pubmed/21406612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00531.2010
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