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Biochemical and pharmacological characterization of AZD1981, an orally available selective DP(2) antagonist in clinical development for asthma

BACKGROUND AND PURPOSE: The discovery of DP(2) as a second receptor for PGD(2) has prompted the search for antagonists as potential novel therapies based on the associations between PGD(2) and disease. Here we describe the biochemical and pharmacological properties of 4-(acetylamino)-3-[(4-chlorophe...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Schmidt, JA, Bell, FM, Akam, E, Marshall, C, Dainty, IA, Heinemann, A, Dougall, IG, Bonnert, RV, Sargent, CA
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Blackwell Publishing Ltd 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605871/
https://ncbi.nlm.nih.gov/pubmed/23146091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12053
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