Biochemical and pharmacological characterization of AZD1981, an orally available selective DP(2) antagonist in clinical development for asthma

BACKGROUND AND PURPOSE: The discovery of DP(2) as a second receptor for PGD(2) has prompted the search for antagonists as potential novel therapies based on the associations between PGD(2) and disease. Here we describe the biochemical and pharmacological properties of 4-(acetylamino)-3-[(4-chlorophe...

詳細記述

保存先:
書誌詳細
主要な著者: Schmidt, JA, Bell, FM, Akam, E, Marshall, C, Dainty, IA, Heinemann, A, Dougall, IG, Bonnert, RV, Sargent, CA
フォーマット: Artigo
言語:Inglês
出版事項: Blackwell Publishing Ltd 2013
主題:
Research Papers
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605871/
https://ncbi.nlm.nih.gov/pubmed/23146091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12053
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