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Effects of an oral CRTH2 antagonist (AZD1981) on eosinophil activity and symptoms in chronic spontaneous urticaria

BACKGROUND: Approximately 50% of patients with chronic spontaneous urticaria (CSU) experience symptoms that are not fully controlled by antihistamines, indicating an unmet clinical need. OBJECTIVE: To evaluate the effects of the selective CRTh2 antagonist AZD1981 on symptoms and targeted leukocytes...

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Detalhes bibliográficos
Publicado no:Int Arch Allergy Immunol
Main Authors: Oliver, Eric Tyrell, Chichester, Kris, Devine, Kelly, Sterba, Patricia Meghan, Wegner, Craig, Vonakis, Becky Marie, Saini, Sarbjit Singh
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500753/
https://ncbi.nlm.nih.gov/pubmed/30879003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000496162
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