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Efficacy and safety of the CRTh2 antagonist AZD1981 as add-on therapy to inhaled corticosteroids and long-acting β(2)-agonists in patients with atopic asthma

OBJECTIVES: To evaluate the efficacy and safety of AZD1981, a potent, specific antagonist of the CRTh2 receptor, as add-on therapy to inhaled corticosteroids (ICS) and long-acting β(2)-agonists (LABA), in patients with persistent asthma with an allergic component. PATIENTS AND METHODS: In this place...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Drug Des Devel Ther
Hauptverfasser: Bateman, Eric D, O’Brien, Christopher, Rugman, Paul, Luke, Sally, Ivanov, Stefan, Uddin, Mohib
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5942163/
https://ncbi.nlm.nih.gov/pubmed/29765200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S147389
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