Biochemical and pharmacological characterization of AZD1981, an orally available selective DP(2) antagonist in clinical development for asthma

BACKGROUND AND PURPOSE: The discovery of DP(2) as a second receptor for PGD(2) has prompted the search for antagonists as potential novel therapies based on the associations between PGD(2) and disease. Here we describe the biochemical and pharmacological properties of 4-(acetylamino)-3-[(4-chlorophe...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Schmidt, JA, Bell, FM, Akam, E, Marshall, C, Dainty, IA, Heinemann, A, Dougall, IG, Bonnert, RV, Sargent, CA
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605871/
https://ncbi.nlm.nih.gov/pubmed/23146091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12053
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados