FFA1-selective agonistic activity based on docking simulation using FFA1 and GPR120 homology models

BACKGROUND AND PURPOSE: The free fatty acid FFA1 receptor and GPR120 are GPCRs whose endogenous ligands are medium- and long-chain FFAs, and they are important in regulating insulin and GLP-1 secretion respectively. Given that the ligands of FFA1 receptor and GPR120 have similar properties, selectiv...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Takeuchi, Masato, Hirasawa, Akira, Hara, Takafumi, Kimura, Ikuo, Hirano, Tatsuya, Suzuki, Takayoshi, Miyata, Naoki, Awaji, Takeo, Ishiguro, Masaji, Tsujimoto, Gozoh
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Publishing Ltd 2013
Onderwerpen:
Research Papers
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605867/
https://ncbi.nlm.nih.gov/pubmed/22639973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02052.x
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items