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Structures of the E46K Mutant-Type α-Synuclein Protein and Impact of E46K Mutation on the Structures of the Wild-Type α-Synuclein Protein

[Image: see text] The E46K genetic missense mutation of the wild-type α-synuclein protein was recently identified in a family of Spanish origin with hereditary Parkinson’s disease. Detailed understanding of the structures of the monomeric E46K mutant-type α-synuclein protein as well as the impact of...

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Detalhes bibliográficos
Main Authors: Wise-Scira, Olivia, Dunn, Aquila, Aloglu, Ahmet K., Sakallioglu, Isin T., Coskuner, Orkid
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605821/
https://ncbi.nlm.nih.gov/pubmed/23374074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn3002027
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