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Geminin becomes activated as an inhibitor of Cdt1/RLF-B following nuclear import
During late mitosis and early interphase, origins of replication become ‘licensed’ for DNA replication by loading Mcm2-7 complexes [1-5]. Mcm2-7 are removed from origins as replication forks initiate replication, thus preventing re-replication of DNA in a single cell cycle. Premature origin licensin...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3605701/ https://ncbi.nlm.nih.gov/pubmed/11967157 |
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